Ingredient Directory
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Dimethyl Isosorbide

1

Safety Flags
CMR: Yes Allergen: 0.30
Safety Notes

Both

Function & Common Use

Function

4:3

Category

5-di-O-methylsorbitol

Common In

No limit

Origin

Solvent / Penetration enhancer

Concentration Limits

India (CDSCO)

None

EU Cosmetics Reg.

None

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked; EU limit reference: None

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Format restriction: No

Baby restriction: No limit

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Dimethyl Isosorbide safe to use in skincare?

Dimethyl Isosorbide has a High concern rating. Both

Is Dimethyl Isosorbide allowed in India?

Dimethyl Isosorbide is currently classified as "Low" under Indian cosmetics regulations. The maximum permitted concentration is None.

What is Dimethyl Isosorbide used for in cosmetics?

Dimethyl Isosorbide functions as: 4:3. It is commonly found in: No limit.

Can Dimethyl Isosorbide cause an allergic reaction?

Yes. Dimethyl Isosorbide has an allergen flag (0.30). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Dimethyl Isosorbide safe for babies?

Dimethyl Isosorbide has baby/child restrictions: No limit. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
SOLV
Data Confidence
Medium
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Low
EU
Solvent / Carrier
US FDA
Permitted
Korea (MFDS)
-
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

EU Annex: Synthetic (plant-derived starch origin)

Identifiers

CAS5306-85-4
EC226-159-8

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